Eliminating Brain Cancer

by harnessing nanotechnology and laser

Brain Cancer Surgery Challenges

Surgeons during brain cancer surgery walk the tight rope of removing enough tumour without damaging the brain. Because brain cancer cells extend like thin tendrils several centimetres into the surrounding brain tissue, it is always a challenge for doctors to remove the entire tumour. Leadinvent Pharma team is working towards making brain surgery better

Before Surgery

Brain cancer is an overgrowth of cells that are typically detected by MRI imaging and surgery is the first step towards eliminating cancer .

After Surgery

However, a small margin of cancer cells escape surgery and in 90% of patients, cancer regrows from the surgical location within 7 months post-surgery.

ENHANCED TUMOR RESECTION

LeadInvent Pharma is leveraging the power of laser, and nanotechnology to develop one of the most advanced gel-based tumor resection treatment modality that would help neuro-oncology surgeons to remove cancer tissue that they are not able to remove using conventional surgical techniques.

GBGel™

At LeadInvent Pharma we have developed a unique medical-grade Gel named GBGelTM which is loaded with powerful cancer-killing light-sensitive nanoparticles.

GBGelTM is made up of FDA approved components and is being designed to be used by surgeons for removing leftover cancer cells that they are not able to remove using conventional surgical techniques.

GBGel™ Method of Application

After removing the maximum tumor, the surgeon would simply spray GBGelTM on the left-over cancer cells. GBGelTM is designed to be quickly absorbed by the left-over cancer cells. Next, the surgeon would illuminate these left-over cancer cells with a low power laser light which would activate the light-sensitive nanoparticles inside the GBGelTM and kills the leftover cancer cells.

About Brain Cancer

Brain cancer is an overgrowth of cells in the brain that forms masses called tumors. Cancerous, or malignant, brain tumors tend to grow very quickly.

Glioblastoma multiforme (GBM) (also called glioblastoma) is a fast-growing glioma that develops from star-shaped glial cells (astrocytes and oligodendrocytes) that support the health of the nerve cells within the brain.

GBM is often referred to as a grade IV astrocytoma. These are the most invasive type of glial tumors, rapidly growing and commonly spreading into nearby brain tissue.

Learn about the team and what drives us

Science is tough and rewarding at the same time. LeadInvent Pharma team brings over 350 man-years of drug discovery and pharma science to the table.

The genesis of our science is in academic research. A team of remarkable scientists at Amrita Nano Science Centre and Erasmus University Rotterdam developed photosensitive nanoparticles with enhanced cancer-killing ability.

LeadInvent Pharma partnered with the team of scientists and neuro-oncology experts to further develop the product and make it available to brain cancer patients